How does CBD works Topically ?
Many folks wonder how does CBD magically works when applied topically. Well first of all there isn't any magic or smoking mirrors when it comes to CBD in general. Since Cannabidiol (CBD) can't enter bloodstream when applied topically, it exerts it medicinal therapeutic effects by penetrating dermal and subdermal layers of our skin tissues.
Our Endocannabinoid System ECS (A Biochemical communication system generated by our brain) naturally produces cannabinoids to keep our physiological activities, functions in balance. When CBD is applied topically it interacts allosterically with CB1 receptors due to its inability to bind directly with CB1 or CB2 receptors. This unique interaction sends signals to these receptors to balance the inflammation.